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What (who) is MALDI imaging - definition
MALDI imaging
MALDI mass spectrometry imaging (MALDI-MSI) is the use of matrix-assisted laser desorption ionization as a mass spectrometry imaging technique in which the sample, often a thin tissue section, is moved in two dimensions while the mass spectrum is recorded. Advantages, like measuring the distribution of a large amount of analytes at one time without destroying the sample, make it a useful method in tissue-based study.
Matrix-assisted laser desorption/ionization
![Diagram of a MALDI TOF instrument. Sample matrix ionized by [[radiant energy]] is ejected from surface. Sample travels into mass analyzer and is substantially detected.](https://commons.wikimedia.org/wiki/Special:FilePath/MALDI TOF EN.png?width=200 "Diagram of a MALDI TOF instrument. Sample matrix ionized by [[radiant energy]] is ejected from surface. Sample travels into mass analyzer and is substantially detected.")
IONIZATION TECHNIQUE THAT USES A LASER ENERGY ABSORBING MATRIX TO CREATE IONS FROM LARGE MOLECULES WITH MINIMAL FRAGMENTATION
Matrix-assisted laser desorption ionization; Maldi; Matrix-assisted Laser Desorption Ionization; MALDI-TOF; MALDI marix; MALDI matrix; MALDI; Matrix-Assisted Laser Desorption/Ionization; Spectrometry, mass, matrix-assisted laser desorption-ionization; Maldi-TOF; MALDI TOF; Matrix-assisted laser desorption ionization-time of flight mass spectrometer; MALDITOF; Matrix-assisted laser desorption-ionization mass spectrometry
In mass spectrometry, matrix-assisted laser desorption/ionization (MALDI) is an ionization technique that uses a laser energy absorbing matrix to create ions from large molecules with minimal fragmentation. It has been applied to the analysis of biomolecules (biopolymers such as DNA, proteins, peptides and carbohydrates) and various organic molecules (such as polymers, dendrimers and other macromolecules), which tend to be fragile and fragment when ionized by more conventional ionization methods.
Breast imaging
NEW QT BREAST IMAGING FDA APPROVED
Imaging of breasts; Imaging of the breast
In medicine, breast imaging is a sub-speciality of diagnostic radiology that involves imaging of the breasts for screening or diagnostic purposes. There are various methods of breast imaging using a variety of technologies as described in detail below.
